Understanding the Functions of Different Antibodies in the Immune System
Learn about the different classes of antibodies and their functions in the immune response.
00:00:01 Learn about the different classes of antibodies and their functions: G, A, D, M, and C. A concise guide to understanding immunoglobulins.
🧬 Antibodies are globular proteins with a three-dimensional structure.
🔍 There are five classes of immunoglobulins or antibodies in our body.
🧪 These classes differ in their constant regions and functions.
00:01:05 Different types and functions of antibodies or immunoglobulins, including their presence in memory B cells, circulation, and mucosal surfaces, as well as their role in neutralization, phagocytosis, complement activation, and conferring immunity to the fetus.
🔍 Antibodies are found on the surface of memory B cells and in circulation during secondary responses.
🔬 Antibodies have neutralizing and opsonizing functions, activate phagocytosis, and activate the complement system.
🔒 Antibodies can cross the placenta and provide immunity to the fetus.
💧 Antibodies are also found in mucosal surfaces and secretions, where they prevent bacterial adherence and neutralize viruses.
00:02:13 Different types of antibodies or immunoglobulins and their functions in immune responses.
🔍 Immunoglobulin D is found on the surface of mature virgin B cells and its functionality is unknown, but it is believed to act as the first receptor for antigens.
🌟 Immunoglobulins bound to mast cells and basophils in the skin, gastrointestinal tract, and respiratory tract play a role in allergic reactions and defense against parasites.
🔁 Immunoglobulin M is found on the surface of memory B cells and in circulation during primary responses. It functions as an immunoglobulin for primary responses.
00:03:19 Different types of antibodies or immunoglobulins and their roles in immune responses, including primary and secondary responses.
🔑 Antibodies in the fetus and neonate have a short lifespan and can neutralize antigens and activate the complement system.
🧬 Immunoglobulins M are involved in primary immune responses, while immunoglobulins G are involved in secondary immune responses.
📊 After initial exposure to an antigen, levels of immunoglobulin M increase, leading to a primary immune response. Subsequently, levels of immunoglobulin G also increase after a period of time, resulting in a secondary immune response.
00:04:21 Different types of antibodies or immunoglobulins, their functions and locations in the body, and the secondary immune response.
🔍 The secondary response to an antigen is faster and stronger than the primary response.
💡 Different types of immunoglobulins play a role in the adaptive immune response.
👍 Further videos on the topic can provide more information and understanding.
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