🔑 Insulin resistance is downstream of mitochondrial dysfunction, which is the root cause of many chronic metabolic diseases.
🔑 The primary driver of insulin resistance is fatty liver disease, which is caused by the accumulation of fat in the liver.
🔑 Multiple factors can contribute to mitochondrial dysfunction, including poor diet, radiation, obesogens, toxins, and air pollution.
Omega-3 fatty acids are essential for heart health, neural structure and function, and are lacking in our diet.
Olive oil, specifically oleic acid, is beneficial for liver function and energy dynamics, but caution must be taken to avoid heating it beyond its smoking point.
Consuming too many polyunsaturated fatty acids can lead to immune system problems, while saturated fat from dairy is anti-inflammatory.
Trans fats, found in many processed foods, can lead to fatty liver and cardiovascular disease.
Trans fats have largely been banned from the food supply, but small amounts can still be present.
Milk contains natural trans fats, but the amount is minimal and not a significant concern.
Milk is a good source of amino acids, fatty acids, and calcium, but the calcium in milk is largely unabsorbable due to the high phosphorus content.
Drinking milk does not reverse osteoporosis, and calcium supplementation alone is not effective.
The China Study book claimed that milk causes cancer based on univariate correlations, but this does not prove causation.
Metabolic health is the true purpose of nutrition, and nutrition is only an adjunct to understanding and improving metabolic health.
Calcium supplements can be beneficial for some people, but their effectiveness and clearance vary, and the role of K2 is unclear.
Algal oil is a source of DHA but not EPA, and plant-based diets may be deficient in EPA, which is important for neurotransmission.
Vegan diets may lack certain amino acids like tryptophan and certain nutrients, and their impact on mitochondrial and metabolic health should be considered.
🧬 Tryptophan and methionine are essential amino acids, with tryptophan being the precursor to serotonin and methionine contributing to antioxidant production.
🐟 Fish is a good source of tryptophan and methionine, which can solve nutritional deficiencies for vegans.
🔥 Mitochondrial dysfunction can be caused by factors like radiation and air pollution, but living at higher altitudes can increase mitochondrial biogenesis.
🍬 Glucose increases mitochondrial function, while fructose inhibits enzymes needed for mitochondrial functioning.
📌 Fructose is harmful and can lead to insulin resistance.
🌾 Starches like amylose and amylopectin in grains affect blood glucose levels differently.
🥦 Fiber is important in reducing glycemic response and maintaining metabolic health.
🍽️ Whole foods and fiber-rich diets are beneficial in managing insulin levels.
🍖 A carnivore diet can be functional, but fiber is crucial for gut health.
🔑 The root cause of insulin resistance is a compromised gut barrier.
🌽 Processed foods with added sugars and refined carbohydrates contribute to insulin resistance.
🍏 Eating whole foods with minimal fructose and fiber helps maintain a healthy gut barrier and prevents insulin resistance.
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