Enhancing Snakebite Treatment with Monoclonal Antibodies and Synthetic Peptides

🐍 Accidents caused by snakes, particularly the species of jararaca, are a neglected tropical disease with significant health implications.

🧪 The project focuses on evaluating the potential of synthetic homologous peptides and monoclonal antibodies in the treatment of jararaca snake venom.

💉 Understanding the enzymes present in the venom and their effects is crucial for developing effective serotherapy for snakebite victims.

🐍 The recommended treatment for snakebite accidents is the pentavalent antibotropic serum, which effectively neutralizes snake venom.

💉 Monoclonal antibodies have shown promise in improving the effectiveness of serotherapy by neutralizing toxins.

🧪 The development of a synthetic region of monoclonal antibodies has demonstrated positive results in enhancing snakebite treatment.

💡 Comparing different venoms and their effects on substrate hydrolysis.

🔬 Studying the stability and mechanisms of peptide inhibitors.

⚙️ Identifying potential regions for the development of protease inhibitors.

🧪 Finding promising tools for serotherapy.