πΌ For over 3000 years, the opium poppy has been used for its pain-relieving properties.
π During the 19th and 20th centuries, synthetic opioids like morphine and heroin were developed.
π Opioids, whether natural or synthetic, are highly effective painkillers but can be addictive.
π In the 80s and 90s, pharmaceutical companies heavily marketed opioid painkillers, leading to a rise in prescription rates and addiction cases.
π§ Opioid drugs bind to opioid receptors in the brain, mimicking the natural pain relief process of endorphins but with stronger and longer-lasting effects.
π« Opioids not only relieve pain, but also affect mood and various bodily functions, with their potency and duration of action surpassing that of naturally occurring molecules in the body.
π§ Opioid drugs stimulate the release of dopamine, which is responsible for feelings of pleasure and euphoria.
π Opioid substances inhibit the release of norepinephrine, affecting alertness, respiration, digestion, and blood pressure.
π Over time, the body develops tolerance to opioids, requiring higher and higher doses to achieve the same effects.
π§ Opioid addiction is caused by an excessive sensitivity to norepinephrine.
βοΈ Stopping opioid use suddenly disrupts the balance and leads to withdrawal symptoms.
β The body takes time to get rid of excess norepinephrine, resulting in a period of extreme sensitivity and withdrawal symptoms.
π‘ Opioid addiction and overdose cases have been increasing in the US and worldwide.
β οΈ Prescription opioids are becoming more regulated, but cases of overdose and addiction, especially among young people, are still rising.
π Naloxone is an effective defense against opioid overdose as it blocks the opioid receptors and reverses excessive doses.
π Opioid addiction treatment programs can be costly and have long waiting lists.
π‘οΈ Withdrawal and prolonged residential stays are challenging for individuals at risk of losing their jobs and housing.
π Medications like methadone and buprenorphine are commonly used in opioid addiction treatment.
π Opioid addiction is a serious problem, with a growing black market.
π There is hope to combat opioid addiction through various treatments and support services.
βοΈ If you or someone you know is struggling with opioid addiction in the United States, seek help from the Department of Health and Human Services.
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